A Secret Weapon For https://www.ceesdekker.net

Using one-molecule optical and AFM imaging and pressure-spectroscopy strategies, we seek to unravel the mechanistic components of the framework and dynamics of chromosomes. Our analysis interests include things like:

But how do morality, the dignity of the individual, my knowledge in the meaning of everyday living, comply with through the movement of atoms? A purely naturalistic standpoint fails listed here; a Christian perspective, I feel, is a much more fair strategy to interpret these elements of truth.’

Dynamics of initiation, termination and reinitiation of DNA translocation through the motor protein EcoR124I

Sculpting nano-electrodes having a transmission electron beam for electrical and geometrical characterization of nanoparticles.

This yielded a breakthrough. Within just a few months, we were in the position to measure transportation through someone single-walled carbon nanotube. According to reduced-temperature experiments by an excellent PhD student in my team, Sander Tans (now a valued colleague and professor at Delft University of Technological innovation with an Energetic research lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being real quantum wires with incredibly lengthy (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.

Immediate immobilization of native yeast iso-one cytochrome c on bare gold: quickly electron relay to redox enzymes and zeptomole protein-movie voltammetry

Because 2000 he moved to solitary-molecule biophysics and nanobiology, with research from DNA supercoiling scientific tests of nucleosomes and DNA fix proteins to DNA translocation by way of nanopores. Not long ago his analysis has focused on researching mobile division with bacteria on chip, though his best curiosity is within the way of noticing synthetic cells.

Atomic drive microscopy shows that vaccinia topoisomerase IB generates filaments on DNA within a cooperative vogue

This "Cited by" depend includes citations to the following content articles in Scholar. Those marked * can be distinctive from the post inside the profile.

‘The fantastically delicate way by which elements in mother nature operate in no way ceases to amaze me. If we resolve the puzzle of how lifestyle arrived into staying, I count on that my amazement in the complexity of generation could have improved and with it my awe for the greatness of your Creator.’

Illustration (4) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is shown in gray, the rim with the pore is highlighted in purple, plus a 3D rendering in the movement with the DNA rod is shown.

2001, discovery of single-electron transistors at space temperature depending on nanotubes; realization of 1st logic circuits with carbon nanotube units; and discovery on the molecular framework of DNA mend enzymes with AFM

Developments in nanotechnology inside the ceesdekker nineties created creating electronic gadgets from single molecules a chance. Cees Dekker recounts how his group produced a space-temperature transistor according to just one carbon nanotube.

2004, discovery of new physics in translocation of DNA by nanopores; very first experimental study of ions conduction in nanofluidic channels; initially electrochemistry with personal one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; to start with electrical docking of microtubules on kinesin-coated nanostructures; 1st biophysics characterization from the mechanical Attributes of double-stranded RNA; and very first one-molecule research of DNA translocation by a restriction-modification enzyme.