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Applying one-molecule optical and AFM imaging and power-spectroscopy methods, we seek to unravel the mechanistic areas of the framework and dynamics of chromosomes. Our study pursuits incorporate:

1996, first mesoscopic cost density waves products; and initial electrical measurements on an individual metallic nanocluster between nanoelectrodes

Dynamics of initiation, termination and reinitiation of DNA translocation because of the motor protein EcoR124I

Nanofabrication of electrodes with sub-5 nm spacing for transportation experiments on single molecules and steel clusters

2010, developed a brand new way (‘wedging transfer’) to control nanostructures; 1st report of DNA translocation by graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into solid-state nanopores

Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

Many associated developments followed, exactly where our group proven diverse transistor variants for example solitary-electron transistors at area temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled many transistors into smaller evidence-of-theory electronic circuits.

Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in gray, the rim on the pore is highlighted in red, and also a 3D rendering from the movement from the DNA rod is shown.

What if, in place of making use of conventional prime-down silicon electronics, transistors might be designed from the bottom up ceesdekker.net applying single natural and organic molecules since the switching features? This idea, which became The idea of today’s discipline of molecular electronics, first emerged while in the 1970s.

Bulk-floor coupling identifies the mechanistic relationship concerning Min-protein patterns in vivo and in vitro

‘The concept that You can find such a factor like a starting, a major bang, is already an interesting signpost to take into account that there was a creator. But additional frequently, and on the basis of pure rationality, I also arrive at a Christian interpretation of reality. An atheistic worldview is actually a naturalistic worldview: basically, there are actually only atoms and natural forces that we are able to measure.

2006, to start with demonstration of molecular sorting inside a lab with a chip utilizing biomotors; discovery of nanobubbles in reliable-point out nanopores; and initial estimate of electrokinetic Vitality conversion in a very nanofluidic channel

Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes

Reliable-condition nanopores have established being a amazingly multipurpose probe for one-molecule Investigation of DNA. I'll explain a number of our new results – specially DNA knots – together with our initiatives to grow the capabilities of sound-state nanopores even additional, within the direction of one-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.